Lately, there has been a new medication known as PARP inhibitors. PARP is an abbreviation for Poly (ADP-Ribose) Polymerase (PARP). This enzyme is responsible for repairing DNA damage in cancer cells in order for cancer to survive. It has been found that in some triple negative tumors, medications that inhibit this PARP have been effective in increasing the response rate to chemotherapy. As one can imagine, if you interfere with a repair mechanism in a cancer cell and in addition to that, add a medication such as chemotherapy that induces DNA damage, you will increase the effectiveness of the chemotherapy. Excerpt from article by Dr. Donald Fleming coming in September.
Posted by Patricia Kirby, Editor Radius Magazine at 8:59:32 AM, EST
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